Mathematical modeling and synthetic biology
نویسندگان
چکیده
منابع مشابه
Mathematical modeling and synthetic biology.
Synthetic biology is an engineering discipline that builds on our mechanistic understanding of molecular biology to program microbes to carry out new functions. Such predictable manipulation of a cell requires modeling and experimental techniques to work together. The modeling component of synthetic biology allows one to design biological circuits and analyze its expected behavior. The experime...
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uniFication Unification involves the integration and synthesis of disparate types of evidence and models. For instance, Darwin unified hybridization, developmental, paleontological, and biogeographical data under a single theory. in mathematical modeling, unification often entails embedding – a subsumption relation allowing for the unification of (i) various mathematical theories/ models and (i...
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Background: As an emerging interdisciplinary area of science with a multitude of potential facilities and applications, synthetic biology integrates different disciplines with one another ranging from basic science to engineering. This interdisciplinary branch therefore encompasses sciences that require specific development and ethical approaches. Materials and Methods: Science management princ...
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Mathematical modeling plays an important and often indispensable role in synthetic biology because it serves as a crucial link between the concept and realization of a biological circuit. We review mathematical modeling concepts and methodologies as relevant to synthetic biology, including assumptions that underlie a model, types of modeling frameworks (deterministic and stochastic), and the im...
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This issue of Cancer Epidemiology, Biomarkers, and Prevention includes a study on mathematical modeling of biological processes. Sokhansanj and Wilson describe a mathematical model that mimics the kinetics of base excision repair and thus permits them to investigate in silico the effects of genetic variation in this important DNA repair pathway (1). Why should epidemiologists have interest in t...
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ژورنال
عنوان ژورنال: Drug Discovery Today: Disease Models
سال: 2008
ISSN: 1740-6757
DOI: 10.1016/j.ddmod.2009.07.002